LPA Disruption with AAV-CRISPR Potently Lowers Plasma Apo(a) in Transgenic Mouse Model: A Proof-of-concept Study
Molecular Therapy Methods & Clinical Development（2022）
Key words
lipoprotein(a),LPA,apolipoprotein(a),liver,gene therapy,adeno-associated virus,somatic genome editing,CRISPR-Cas9,AAV-CRISPR,atherosclerosis
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