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Dysfunctional Extracellular Matrix Remodeling Supports Perianal Fistulizing Crohn's Disease by a Mechanoregulated Activation of the Epithelial-to-Mesenchymal Transition

Giulia Rizzo,Federica Rubbino,Sudharshan Elangovan,Giusy Sammarco,Sara Lovisa,Silvia Restelli,Samuel Elias Pineda Chavez,Luca Massimino,Luigi Lamparelli,Marianna Paulis,Annalisa Maroli,Giulia Roda,Mohammad Shalaby,Michele Carvello,Caterina Foppa, Sheona P. Drummond,Paola Spaggiari,Federica Ungaro,Antonino Spinelli,Alberto Malesci,Alessandro Repici,Anthony J. Day,Alessandro Armuzzi,Silvio Danese,Stefania Vetrano

Cellular and Molecular Gastroenterology and Hepatology（2022）

Cited 5|Views65
Key words
Perianal Fistula,Crohn′s Disease,TSG-6,Extracellular Matrix,EMT
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