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Loci for Insulin Processing and Secretion Provide Insight into Type 2 Diabetes Risk

K. Alaine Broadaway,Xianyong Yin,Alice Williamson,Victoria A. Parsons,Emma P. Wilson,Anne H. Moxley,Swarooparani Vadlamudi,Arushi Varshney,Anne U. Jackson,Vasudha Ahuja,Stefan R. Bornstein,Laura J. Corbin,Graciela E. Delgado,Om P. Dwivedi,Lilian Fernandes Silva,Timothy M. Frayling,Harald Grallert,Stefan Gustafsson,Liisa Hakaste,Ulf Hammar,Christian Herder,Sandra Herrmann,Kurt Hojlund,David A. Hughes,Marcus E. Kleber,Cecilia M. Lindgren,Ching-Ti Liu,Jian'an Luan,Anni Malmberg,Angela P. Moissl,Andrew P. Morris,Nikolaos Perakakis,Annette Peters,John R. Petrie,Michael Roden,Peter E. H. Schwarz,Sapna Sharma,Angela Silveira,Rona J. Strawbridge,Tiinamaija Tuomi,Andrew R. Wood,Peitao Wu,Bjorn Zethelius,Damiano Baldassarre,Johan G. Eriksson,Tove Fall,Jose C. Florez,Andreas Fritsche,Bruna Gigante,Anders Hamsten,Eero Kajantie,Markku Laakso,Jari Lahti,Deborah A. Lawlor,Lars Lind,Winfried Maerz,James B. Meigs,Johan Sundstrom,Nicholas J. Timpson,Robert Wagner,Mark Walker,Nicholas J. Wareham,Hugh Watkins,Ines Barroso,Stephen O'Rahilly,Niels Grarup,Stephen CJ. Parker,Michael Boehnke,Claudia Langenberg,Eleanor Wheeler,Karen L. Mohlke

The American Journal of Human Genetics（2023）

Cited 9|Views156
Key words
GWAS,proinsulin,meta-analysis,type 2 diabetes,colocalization,eQTL,enhancer,conditional,signal,fine-mapping
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