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Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists

Arun Chandramohan,Hubert Josien,Tsz Ying Yuen,Ruchia Duggal,Diana Spiegelberg,Lin Yan, Yu-Chi Angela Juang,Lan Ge,Pietro Aronica,Kristal Kaan,Yee Hwee Lim,Andrea Peier,Brad Sherborne,Jerome Hochman,Songnian Lin,Kaustav Biswas,Brian Henry,Marika Nestor,Chandra S Verma,David Lane,Tomi Sawyer,Robert Garbaccio,Srinivasaraghavan Kannan,Srinivasaraghavan Kannan,Christopher J. Brown,Charles W Johannes,Anthony William Partridge

bioRxiv (Cold Spring Harbor Laboratory)（2023）

Cited 1|Views30
Key words
peptides,mdm2/x,antagonists,design-rules,alpha-helical,on-target
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