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Mechanistic Incorporation of FcRn Binding in Plasma and Endosomes in a Whole Body PBPK Model for Large Molecules

de Witte Wilhelmus E. A.,Avery Lindsay B.,Mackness Brian C., Van Bogaert Tom,Park Anna, Sargentini-Maier Maria Laura

Journal of Pharmacokinetics and Pharmacodynamics（2023）

Cited 2|Views6
Key words
PBPK,PK-Sim®,FcRn,Binding,Model
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