Supplementary figure S3 from CD4⁺ T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

In vitro toxicity of Trp-specific T cells against wild type and MHC II-deficient B16 melanoma variants. Results of adoptive T cell therapy experiments in mice challenged with wild type B16 tumor cells.