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Stabilization of the Dimeric State of SARS-CoV-2 Main Protease by GC376 and Nirmatrelvir

Alessandro Paciaroni,Valeria Libera,Francesca Ripanti,Andrea Orecchini,Caterina Petrillo,Daniela Francisci,Elisabetta Schiaroli,Samuele Sabbatini,Anna Gidari,Elisa Bianconi,Antonio Macchiarulo,Rohanah Hussain,Lucia Silvestrini,Paolo Moretti,Norhan Belhaj,Matteo Vercelli,Yessica Roque,Paolo Mariani,Lucia Comez,Francesco Spinozzi

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES（2023）

Cited 4|Views54
Key words
main protease,dimerization,COVID-19,SARS-CoV-2,inhibitor,Paxlovid,PF-07321332,small angle X-ray scattering,microscale thermophoresis,circular dichroism
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