Single-cell Sequencing Reveals the Immune Microenvironment Landscape Related to Anti-Pd-1 Resistance in Metastatic Colorectal Cancer with High Microsatellite Instability

Tao Wu,Xuan Zhang, Xinxing Liu,Xinyi Cai,Tao Shen,Dingguo Pan,Rui Liang,Rong Ding,Ruixi Hu,Jianhua Dong,Furong Li,Jinsha Li,Lin Xie, Chunlong Wang, Shilei Geng, Zhaoyu Yang,Lu Xing,YunFeng Li

BMC Medicine（2023）

Cited 9|Views25

Key words

Metastatic colorectal cancer (mCRC),Programmed cell death protein-1(PD-1),Interleukin-1 beta (IL-1β),Myeloid-derived suppressor cells (MDSCs),microsatellite instability-high (MSI-H),Deficient mismatch repair (dMMR)

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