Breast Cancer Genomes from CHEK2 C.1100delc Mutation Carriers Lack Somatic TP53 Mutations and Display a Unique Structural Variant Size Distribution Profile.

Marcel Smid,Marjanka K. Schmidt,Wendy J. C. Prager-van der Smissen,Kirsten Ruigrok-Ritstier,Maartje A. C. Schreurs,Sten Cornelissen, Aida Marsal Garcia,Annegien Broeks,A. Mieke Timmermans,Anita M. A. C. Trapman-Jansen,J. Margriet Collée,Muriel A. Adank,Maartje J. Hooning,John W. M. Martens,Antoinette Hollestelle

BREAST CANCER RESEARCH（2023）

引用 3|浏览44

关键词

CHEK2,Whole-genome sequencing,Somatic cancer genome,Mutational landscape,TP53 mutation,Structural variation,Size distribution,Chromothripsis,Whole-genome duplication,Breast cancer

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