Dose Imbalance of DYRK1A Kinase Causes Systemic Progeroid Status in Down Syndrome by Increasing the Un-Repaired DNA Damage and Reducing LaminB1 Levels.
EBIOMEDICINE（2023）
Key words
Down syndrome,Down syndrome critical region,Chromosome 21,Ageing,DYRK1A,DYRK1A inhibitors,LaminB1,IgG glycan
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