Radiocomplexation, Biological Evaluation, and Characterization of [ 99m Tc]-5-[(3-Carboxy-4-hydroxyphenyl)diazenyl]-2-hydroxybenzoic Acid As a Novel Agent for Imaging of Ulcerative Colitis in Mice

M. H. Sanad,H. M. Eyssa,F. A. Marzook,A. B. Farag, A. Elrefaei,A. S. M. Fouzy,S. B. Challan

Radiochemistry（2023）

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摘要

A procedure was developed for preparing [99mTc]-tricarbonyl-5-[(3-carboxy-4-hydroxyphenyl)diazenyl]-2-hydroxybenzoic acid complex ([99mTc]-tricarbonyl-Olsalazine), for ulcerative colitis (UC) imaging. High yield and 98.5

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关键词

Olsalazine,[99mTc]tricarbonyl precursor,bioevaluation,mice,PPARγ receptor,ulcerative colitis imaging

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