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Impact of Individual Level Uncertainty of Lung Cancer Polygenic Risk Score (PRS) on Risk Stratification

Xinan Wang, Ziwei Zhang,Yi Ding,Tony Chen,Lorelei Mucci,Demetrios Albanes,Maria Teresa Landi,Neil E. Caporaso,Stephen Lam,Adonina Tardon,Chu Chen,Stig E. Bojesen,Mattias Johansson,Angela Risch,Heike Bickeböller,H-Erich Wichmann,Gadi Rennert,Susanne Arnold,Paul Brennan,James D. McKay,John K. Field,Sanjay S. Shete,Loic Le Marchand,Geoffrey Liu,Angeline S. Andrew,Lambertus A. Kiemeney,Shan Zienolddiny-Narui,Annelie Behndig,Mikael Johansson,Angie Cox,Philip Lazarus,Matthew B. Schabath,Melinda C. Aldrich,Rayjean J. Hung,Christopher I. Amos,Xihong Lin,David C. Christiani

Genome Medicine（2024）

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关键词
Non-small cell lung cancer (NSCLC),Polygenic risk score (PRSs),Cancer control,Population science,Genetic epidemiology
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