APOE Christchurch-mimetic Therapeutic Antibody Reduces APOE-mediated Toxicity and Tau Phosphorylation.

Claudia Marino,Paula Perez-Corredor,Michael O'Hare, Annie Heuer,Natalia Chmielewska,Harper Gordon,Anita S. Chandrahas,Lucia Gonzalez-Buendia,Santiago Delgado-Tirado, Tri H. Doan, Timothy E. Vanderleest,Said Arevalo-Alquichire, Robert A. Obar, Carolina Ortiz-Cordero,Andres Villegas,Diego Sepulveda-Falla,Leo A. Kim,Francisco Lopera,Robert Mahley,Yadong Huang,Yakeel T. Quiroz,Joseph F. Arboleda-Velasquez

ALZHEIMERS & DEMENTIA（2024）

Cited 4|Views33

Key words

Alzheimer's disease,ApoE Christchurch,ApoE,Apolipoprotein E,drug development,heparan,sulfate proteoglycan,heparin,HSPG,tau phosphorylation,tauopathy,therapeutic antibody

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