Reversible and Irreversible Inhibitors of Coronavirus Nsp15 Endoribonuclease

Jerry Chen,Rabih Abou Farraj,Daniel Limonta,Seyed Amir Tabatabaei Dakhili,Evan M. Kerek, Ashim Bhattacharya,Filip M. Reformat, Ola M. Mabrouk,Benjamin Brigant,Tom A. Pfeifer,Mark T. McDermott,John R. Ussher,Tom C. Hobman,J. N. Mark Glover,Basil P. Hubbard

JOURNAL OF BIOLOGICAL CHEMISTRY（2023）

Cited 2|Views36

Key words

SARS-CoV-2,COVID-19,immune evasion,coronaviruses,nidoviruses,RNA endonucleases,Nsp15,high-throughput chemical screen,small-molecule inhibitors,COVID-19 therapeutics,hexachlorophene,IPA-3

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