Differential Network Analysis of ROS1 Inhibitors Reveals Lorlatinib Polypharmacology Through Co-Targeting PYK2.
CELL CHEMICAL BIOLOGY（2024）
关键词
Lorlatinib,ROS1,non-small cell lung cancer,polypharmacology,chemoproteomics,phosphoproteomics,network analysis,PYK2,SRC,synergy
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