Community Recommendations on Cryoem Data Archiving and Validation

IUCRJ(2024)

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摘要
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and the resulting consensus recommendations. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.
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关键词
cryogenic-specimen electron microscopy,data archiving,validation,quality control,Electron Microscopy Data Bank,Protein Data Bank,single-particle cryoEM,databases,bioinformatics,structure determination
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