Supplementary Figure 1 from <i>kras</i> Codon 12 and 13 Mutations in Relation to Disease-Free Survival in ≪i>braf</i>–wild-Type Stage III Colon Cancers from an Adjuvant Chemotherapy Trial (N0147 Alliance)

Harry H. Yoon, David Tougeron,Qian Shi, Steven R. Alberts, Michelle R. Mahoney, Garth D. Nelson, Suresh Nair,Stephen N. Thibodeau, Richard M. Goldberg, Daniel J. Sargent,Frank A. Sinicrope

openalex(2023)

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摘要
PDF file - 108KB, Predictive value of specific KRAS mutations in patients with BRAF-wild type resected stage III colon cancer treated with adjuvant FOLFOX chemotherapy with vs without cetuximab. Unadjusted hazard ratios (HR) for disease-free survival by KRAS mutation strata are shown for patients who were randomized during the period when KRAS-mutated and -wild type tumors were eligible. HR < 1 indicates benefit from cetuximab. No estimates produced due to insufficient sample size in one subgroup.
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