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In Vitro Generated Antibodies Guide Thermostable ADDomer Nanoparticle Design for Nasal Vaccination and Passive Immunization Against SARS-CoV-2

Dora Buzas,Adrian H. Bunzel,Oskar Staufer,Emily J. Milodowski,Grace L. Edmunds,Joshua C. Bufton,Beatriz V. Vidana Mateo,Sathish K. N. Yadav,Kapil Gupta,Charlotte Fletcher,Maia K. Williamson,Alexandra Harrison,Ufuk Borucu,Julien Capin,Ore Francis,Georgia Balchin,Sophie Hall, Mirella V. Vega,Fabien Durbesson, Srikanth Lingappa,Renaud Vincentelli,Joe Roe,Linda Wooldridge,Rachel Burt,Ross J. L. Anderson,Adrian J. Mulholland, Jonathan Hare,Mick Bailey,Andrew D. Davidson,Adam Finn,David Morgan,Jamie Mann,Joachim Spatz,Frederic Garzoni,Christiane Schaffitzel,Imre Berger

ANTIBODY THERAPEUTICS（2023）

Cited 1|Views40
Key words
pandemic preparedness,ADDomer,protein nanoparticle design,in vitro selection (Ribosome Display),Gigabody superbinder,synthetic vaccine,electron cryo-microscopy (cryo-EM),respiratory viral diseases
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