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Assessment of Mendelian and Risk-Factor Genes in Alzheimer Disease: A Prospective Nationwide Clinical Utility Study and Recommendations for Genetic Screening

Gael Nicolas,Aline Zarea,Morgane Lacour,Olivier Quenez,Stephane Rousseau,Anne-Claire Richard,Antoine Bonnevalle,Catherine Schramm,Robert Olaso,Florian Sandron,Anne Boland,Jean-Francois Deleuze,Daniela Andriuta,Pierre Anthony,Sophie Auriacombe,Anna-Chloe Balageas,Guillaume Ballan,Melanie Barbay,Yannick Beiot,Serge Belliard,Marie Benaiteau,Karim Bennys,Stephanie Bombois,Claire Boutoleau-Bretonniere,Pierre Branger,Jasmine Carlier, Leslie Cartz-Piver,Pascaline Cassagnaud,Mathieu-Pierre Ceccaldi,Valerie Chauvire,Yaohua Chen,Julien Cogez,Emmanuel Cognat, Fabienne Contegal-Callier, Lea Corneille,Philippe Couratier,Benjamin Cretin,Charlotte Crinquette,Benjamin Dauriat,Sophie Dautricourt,Vincent de la Sayette, Astrid de Liege, Didier Deffond,Florence Demurger,Vincent Deramecourt,Celine Derollez,Elsa Dionet,Martine Doco Fenzy, Julien Dumurgier,Anais Dutray,Frederique Etcharry-Bouyx,Maite Formaglio,Audrey Gabelle, Anne Gainche-Salmon,Olivier Godefroy,Mathilde Graber, Chloe Gregoire,Stephan Grimaldi, Julien Gueniat,Claude Gueriot,Virginie Guillet-Pichon,Sophie Haffen, Cezara-Roxana Hanta, Clemence Hardy,Geoffroy Hautecloque,Camille Heitz,Claire Hourregue,Therese Jonveaux,Snejana Jurici,Lejla Koric,Pierre Krolak-Salmon,Julien Lagarde,Helene-Marie Lanoiselee,Brice Laurens,Isabelle Le Ber,Gwenael Le Guyader,Amelie Leblanc,Thibaud Lebouvier,Richard Levy, Anais Lippi,Marie-Anne Mackowiak,Eloi Magnin,Cecilia Marelli,Olivier Martinaud,Aurelien Maureille,Raffaella Migliaccio, Emilie Milongo-Rigal,Sophie Mohr,Helene Mollion,Alexandre Morin, Julia Nivelle, Camille Noiray,Pauline Olivieri,Claire Paquet,Jeremie Pariente,Florence Pasquier,Alexandre Perron,Nathalie Philippi,Vincent Planche,Helene Pouclet-Courtemanche,Marie Rafiq,Adeline Rollin-Sillaire,Carole Roue-Jagot,Dario Saracino,Marie Sarazin,Mathilde Sauvee,Francois Sellal,Marc Teichmann,Christel Thauvin,Quentin Thomas,Camille Tisserand, Cedric Turpinat,Laurene Van Damme,Olivier Vercruysse,Nicolas Villain,Nathalie Wagemann,Camille Charbonnier,David Wallon

GENETICS IN MEDICINE（2024）

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Key words
Alzheimer disease,Risk variant,Pathogenic variant,Exome,Clinical utility
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