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Discovery of a Small Molecule Activator of Slack (kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine‐Independent and Chronic Itch

Annika Balzulat,W. Felix Zhu,Cathrin Flauaus,Victor Hernandez-Olmos,Jan Heering,Sunesh Sethumadhavan,Mariam Dubiel,Annika Frank,Amelie Menge,Maureen Hebchen,Katharina Metzner,Ruirui Lu,Robert Lukowski,Peter Ruth,Stefan Knapp,Susanne Mueller,Dieter Steinhilber,Inga Haenelt,Holger Stark,Ewgenij Proschak,Achim Schmidtko

ADVANCED SCIENCE（2024）

Cited 0|Views18
Key words
drug development,itch,kcnt1,slack,target validation
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