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Structure-guided Optimization of 3-Hydroxybenzoisoxazole Derivatives As Inhibitors of Aldo-keto Reductase 1C3 (AKR1C3) to Target Prostate Cancer.

Agnese Chiara Pippione,Sandra Kovachka, Chiara Vigato,Laura Bertarini, Iole Mannella,Stefano Sainas,Barbara Rolando,Enrica Denasio, Helen Piercy-Mycock, Linda Romalho, Edoardo Salladini,Salvatore Adinolfi,Daniele Zonari,Caterina Peraldo-Neia,Giovanna Chiorino,Alice Passoni,Osman Asghar Mirza,Karla Frydenvang,Klaus Pors,Marco Lucio Lolli,Francesca Spyrakis,Simonetta Oliaro-Bosso,Donatella Boschi

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

Cited 0|Views25
Key words
AKR1C3 inhibitors,Prostate cancer,Benzoisoxazoles,X-ray crystallography
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