Substrate Promiscuity of Key Resistance P450s Confers Clothianidin Resistance While Increasing Chlorfenapyr Potency in Malaria Vectors

Magellan Tchouakui,Sulaiman S. Ibrahim, Mersimine K. Mangoua,Riccado F. Thiomela,Tatiane Assatse, Sonia L. Ngongang-Yipmo,Abdullahi Muhammad,Leon J. M. Mugenzi,Benjamin D. Menze,Themba Mzilahowa,Charles S. Wondji

Cell reports（2024）

Cited 0|Views5

Key words

malaria,Anopheles funestus,cross-resistance,CYP6P9a and CYP6P9b,chlorfenapyr,neonicotinoid,metabolism assay,RNA interference,insecticide resistance markers,experimental huts

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