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Polygenic Risk Scores from Multi-Ancestry GWAS of >450 Phenotypes in the Pan-UK Biobank Project Offer Insights into Impacts of Genetic Architecture, Ancestry, and Statistical Methodology on Prediction

Kristin Tsuo,Ying Wang,Konrad Karczewski,Rahul Gupta,Masahiro Kanai,Nikolas Baya,Raymond Walters,Patrick Turley,Shawneequa Callier,Duncan Palmer,Jacqueline Goldstein,Gopal Sarma,Matthew Solomonson,Nathan Cheng,Wenhan Lu,Sam Bryant,Claire Churchhouse,Caroline Cusick,Daniel King,Timothy Poterba,John Compitello,Wei Zhou,Cotton Seed,Mark Daly,Hilary Finucane,Benjamin Neale,Elizabeth Atkinson,Alicia Martin

EUROPEAN JOURNAL OF HUMAN GENETICS（2024）

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