Transition-Metal-Free Synthesis of a Densely Functionalized Benzodioxole Intermediate Toward Lotiglipron

Jimmy Wang, James Clarke,Matthew Badland, Brian Broadbelt, Louise F. Dow,Harriet A. M. Fenton, Daniel A. Laity,Jinu S. Mathew, Emily K. Rose, Neringa Tamosiunaite,Steven J. R. Twiddle,Robert Walton

Organic Process Research & Development（2024）

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Key words

benzodioxole,lotiglipron,transition metalfree,alkylation,pyridine

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