CRISPR-mediated Megabase-Scale Transgene De-Duplication to Generate a Functional Single-Copy Full-Length Humanized DMD Mouse Model
BMC BIOLOGY（2024）
Key words
CRISPR-Cas9,Duchenne muscular dystrophy,Humanized mouse model,Zygote microinjection,Transgenic mouse model,Dystrophin,Megabase scale deletion,Nanopore sequencing,Illumina sequencing,Gene editing
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