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A Single Administration of an Epigenetic Editor Targeting Human PCSK9 Robustly and Durably Lowers Cholesterol In Vivo

Frederic Tremblay, Kenneth Kelly, Shrijal Shah, Gabriel El Sebae,Chih-Wei Ko,Scott Clarkson,Ricardo N. Ramirez,Erica Hildebrand, Narayan Wong, Shane Wright,Mary Morrison,Sahar Abubucker,Ari Friedland,Morgan Maeder,John Xiong

CIRCULATION RESEARCH（2023）

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Key words
Epigenetics,Cholesterol,LDL,Arteriosclerosis,Cardiovascular disease
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