Engineering Memory T Cells As a Platform for Long-Term Enzyme Replacement Therapy in Lysosomal Storage Disorders

Evan W. Kleinboehl,Kanut Laoharawee, Jacob D. Jensen,Joseph J. Peterson,Nicholas J. Slipek,Bryce J. Wick,Matthew J. Johnson,Beau R. Webber,Branden S. Moriarity

MOLECULAR THERAPY（2024）

Cited 0|Views25

Key words

CRISPR-Cas9,genome engineering,memory T cells,lysosomal storage disorders,mucopolysaccharidosis type I,gene therapy,homology-directed repair,Hurler syndrome

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined