Tyrosine Kinase 2 Modulates Splenic B Cells Through Type I IFN and TLR7 Signaling

Irene Bodega-Mayor,Pablo Delgado-Wicke,Alejandro Arrabal, Estíbaliz Alegría-Carrasco, Ana Nicolao-Gómez, Marta Jaén-Castaño, Cristina Espadas,Ana Dopazo,Enrique Martín-Gayo,María Luisa Gaspar,Belén de Andrés,Elena Fernández-Ruiz

EUROPEAN JOURNAL OF IMMUNOLOGY（2024）

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Key words

Tyrosine kinase 2 (TYK2),TYK2-deficient mice,Aged B cells,Marginal zone B cells,Follicular B cells,Toll-like receptor 7 (TLR7),Type I IFN,IFNα,β receptor

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