Damaging mutations in LXRα uncouple lipogenesis from hepatotoxicity and implicate hepatic cholesterol sensing in human liver health
Sam M Lockhart,Milan Muso,Ilona Zvetkova,Brian YH Lam,Alessandra Ferrari,Erik Schoenmakers,Katie Duckett,Jack Leslie,Beatriz Romartínez-Alonso,John Tadross,Raina Jia,Eugene J. Gardner,Katherine Kentistou,Yajie Zhao,Felix Day,Alexander Mörseburg,Kara Rainbow,Debra Rimmington, Matteo Mastantuoni,James Harrison,Meritxell Nus, Khalid Guma’a, Sam Sherratt-Mayhew, Xiao Jiang,Katherine R Smith,Dirk S Paul, Ben Jenkins,Albert Koulman,Maik Pietzner,Claudia Langenberg,Nick Wareham,Giles S Yeo,Krishna Chatterjee,John Schwabe,Fiona Oakley,Derek Mann,Peter Tontonoz, Tony Coll,Ken Ong,John R.B. Perry,Stephen O’Rahilly crossref（2024）
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