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New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs

Thalia Delgado, Denisa Vesela,Hana Dostalova,Vladimir Krystof,Veronika Vojackova,Radek Jorda,Alejandro Castro,Jeanluc Bertrand,Gildardo Rivera,Mario Faundez,Miroslav Strnad,Christian Espinosa-Bustos,Cristian O. Salas

PHARMACEUTICS（2024）

Cited 0|Views9
Key words
chronic myeloid leukemia,TKI-resistant cells,Bcr-Abl inhibitors,purine derivatives,in silico studies
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