COVID-19 in an Adolescent with Aplastic Anemia Undergoing Immunosuppressive Therapy: a Case Report and Details of Antibody Testing for SARS-CoV-2

Authorea (Authorea)(2024)

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摘要
The clinical course of COVID-19 in pediatric patients with aplastic anemia (AA) have not been thoroughly investigated. We report a case of COVID-19 in a 15-year-old male with AA treated via immunosuppressive therapy. The patient initially presented with a fever and mild sore throat. He continued cyclosporine treatment, and his symptoms improved with a single dose of hydrocortisone. Antibody testing showed increased anti-S1 and anti-RBD IgA levels, followed by elevation of anti-S1 and anti-N IgM/IgG levels. Our results suggest that AA is not necessarily associated with a higher risk of severe COVID-19.
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