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Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics As Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes

Federica Matteucci,Marta Ferrati,Eleonora Spinozzi, Alessia Piergentili,Fabio Del Bello,Gianfabio Giorgioni,Leonardo Sorci,Riccardo Petrelli,Loredana Cappellacci

Pharmaceuticals（2024）

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Key words
NAD metabolism,anticancer therapy,NAD analogues,NMNAT inhibitors,inhibitor design,dinucleotides
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