The Mitochondrial TSPO Ligand Atriol Mitigates Metabolic-Associated Steatohepatitis by Downregulating CXCL1

Yuchang Li,Liting Chen,Chantal Sottas, Mahima Chandrakant Raul, Nrupa Dinesh Patel, Janaki Ramulu Bijja, S. Kaleem Ahmed,Audrey Kapelanski-Lamoureux,Anthoula Lazaris,Peter Metrakos, Alexander Zambidis,Shefali Chopra,Meng Li,Go Sugahara,Takeshi Saito,Vassilios Papadopoulos

Metabolism（2024）

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Key words

ADME (Absorption, Distribution, Metabolism, Excretion),Pharmacokinetic profile,Crown-like structures,Fibrosis,Myeloperoxidase,Proinflammation,Mitochondrial function

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