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Virus-like Particles Displaying the Mature C-terminal Domain of Filamentous Hemagglutinin Are Immunogenic and Protective Against Bordetella Pertussis Respiratory Infection in Mice

Gage M. Pyles,Annalisa B. Huckaby,Maria de la Paz Gutierrez,William T. Witt,Margalida Mateu-Borras,Spencer R. Dublin, Carleena Rocuskie-Marker, Bethany N. Sesti, Kerrington Peasak,Graham J. Bitzer,Nathaniel Rader,Kelly L. Weaver,Dylan T. Boehm, Nicholas Fitzgerald, Joshua Chapman, Samuel Ulicny,F. Heath Damron,Mariette Barbier

INFECTION AND IMMUNITY（2024）

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Key words
Bordetella pertussis,whooping cough,pertussis,DTaP,pertussis toxin,VLP,FHA,vaccines,bacterial challenge,pertussis mouse model,vaccine evaluation
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