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Molecular Design and Evaluation of Aza-Polycyclic Carbamoyl Pyridones As HIV-1 Integrase Strand Transfer Inhibitors

Toshiyuki Akiyama,Brian A. Johns,Yoshiyuki Taoda,Hiroshi Yoshida,Teruhiko Taishi,Takashi Kawasuji,Hitoshi Murai,Tomokazu Yoshinaga,Akihiko Sato,Takahiro Seki, Mikiko Koyama,Shigeru Miki,Shinobu Kawauchi-Miki,Akemi Kagitani-Suyama,Tamio Fujiwara

Bioorganic & Medicinal Chemistry Letters（2024）

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Key words
HIV integrase,INSTIs (integrase strand transfer inhibitors),Long-acting,Scaffold hopping
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