Auto-Regulatory Mechanism of Enzyme Activity by the Nuclear Localization Signal of Lysine Specific Demethylase 1

Dulmi Senanayaka,Danyun Zeng, Sahar Alishiri,William J. Martin, Khadijah I. Moore, Roshni Patel,Zigmund Luka,Alexander Hirschi,Nicholas J. Reiter

JOURNAL OF BIOLOGICAL CHEMISTRY（2024）

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Key words

intrinsically disordered protein,nuclear localization signal (NLS),structural biology,histone demethylase,nucleosome,inhibition mechanism,NMR,autoinhibition

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