Efficacy and Safety of Combining Short-Course Neoadjuvant Chemoradiotherapy with Envafolimab in Locally Advanced Rectal Cancer Patients with Microsatellite Stability: A Phase II PRECAM Experimental Study

Fei Wang,Chuanxi Lai,Yiming Lv, Feixiang Zhang,Liming Shi, Yunfei Wang, Yanbin Shen,Lingna Xu,Peng Hu,Wen Tang,Dengyong Xu,Gaoyang Cao,Lina Shan,Xiya Jia,Yiyi Chen,David W. Larson,Da Wang,Weifeng Lao,Hongcang Gu,Xiaonan Sun,Xuefeng Huang,Sheng Dai

INTERNATIONAL JOURNAL OF SURGERY（2025）

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Key words

envafolimab,immune checkpoint inhibitor,locally advanced rectal cancer,microsatellite stability,pathologic complete response,preoperative neoadjuvant therapy,short-course radiotherapy

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