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Multivalent CXCR4-targeting Nanobody Formats Differently Affect Affinity, Receptor Clustering, and Antagonism

Stephanie M. Anbuhl, Xavier Dervillez,Saskia Neubacher,Angela I. Schriek,Vladimir Bobkov,Steven W. de Taeye,Martyna Szpakowska,Marco Siderius, Tom N. Grossmann,Andy Chevigne,Martine J. Smit,Raimond Heukers

Biochemical Pharmacology（2024）

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关键词
Nanobody,Nanobody-Fc,Affinity,Avidity,Multivalency,CXCR4
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