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Tp53 R217H and R242H Mutant Zebrafish Exhibit Dysfunctional P53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes

Kim Kobar,Lissandra Tuzi, Jennifer A. Fiene, Erin Burnley, Kristianne J. C. Galpin,Craig Midgen,Brianne Laverty,Vallijah Subasri, Timmy T. Wen,Martin Hirst,Michelle Moksa,Annaick Carles,Qi Cao,Adam Shlien,David Malkin,Sergey Prykhozhij,Jason N. Berman

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE（2025）

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关键词
Li-Fraumeni syndrome,p53,tp53,Zebrafish,Cancer,Cancer predisposition
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