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Rethinking the Residual Approach: Leveraging Statistical Learning to Operationalize Cognitive Resilience in Alzheimer’s Disease

Colin Birkenbihl, Madison Cuppels,Rory T. Boyle,Hannah M. Klinger,Oliver Langford,Gillian T. Coughlan,Michael J. Properzi,Jasmeer Chhatwal,Julie C. Price,Aaron P. Schultz,Dorene M. Rentz,Rebecca E. Amariglio,Keith A. Johnson,Rebecca F. Gottesman,Shubhabrata Mukherjee,Paul Maruff,Yen Ying Lim,Colin L. Masters,Alexa Beiser,Susan M. Resnick,Timothy M. Hughes, Samantha Burnham,Ilke Tunali,Susan Landau,Ann D. Cohen,Sterling C. Johnson,Tobey J. Betthauser,Sudha Seshadri,Samuel N. Lockhart,Sid E. O’Bryant,Prashanthi Vemuri,Reisa A. Sperling,Timothy J. Hohman,Michael C. Donohue,Rachel F. Buckley

Brain Informatics（2025）

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关键词
Cognitive resilience,Alzheimer’s disease,Dementia,Machine learning,Artificial intelligence,Cognitive reserve,Pathology resistance,Cognitive decline
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