Investigating the Prevalence of Thyroid Disorders and Their Contributing Factors in Iran: A Cross-Sectional Analysis

Background: Thyroid problems have been reported in over 110 countries worldwide. In some countries, the prevalence of known thyroid disorders has been reported to be as high as 18.9%. Given that thyroid dysfunction can adversely affect adult health, we aimed to assess the prevalence of thyroid disease and related factors in the Fasa Persian Cohort Study Centre.Methods: This cross-sectional study was conducted in southwestern Iran. It included 10,132 participants, with an average age of 48.63. Demographic and clinical data were used as baseline cohort information. Multiple logistic regression analysis was conducted to investigate factors associated with thyroid disease.Results: The prevalence of thyroid disease was 8.8%. According to the results of the multiple analysis gender (AORfemale/ male=5.94.95% CI: 1.66-7.58), education level (AOR Literate/ Illiterate=1.21, 95% CI: 1.04-1.40), diabetes (AORYes/No=1.32, 95% CI: 1.09-1.69), hypertension (AORYes/No=1.38, 95% CI: 1.17-1.64), depression (AORYes/No=1.72, 95% CI: 1.38-2.13) were associated with the odds of thyroid disease. Also, metabolic equivalent task (MET) (AOR=0.99, 95% CI: 0.02-0.083), duration sleep (AOR6- 7/≤5=0.77, 95% CI: 0.61-0.97), and duration sleep (AOR≥8/≤5=0.80, 95% CI: 0.64-0.99) were identified as protective factors in the study.Conclusion: This study’s findings indicated that the total prevalence of thyroid disease in adults was 8.8%. The researchers found that gender, education level, hypertension, diabetes, and depression increased the odds of thyroid disease. In addition, duration of sleep and MET were identified as protective factors. Further consideration of thyroid disease and screening for this population is recommended.