Research Progress of Antibody–drug Conjugates in Gynecologic Cancer

Dongdong Xu,Zhe-Sheng Chen, Xuanwei Peng,Zhongqiu Lin,Huaiwu Lu

Holistic Integrative Oncology(2024)

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摘要
Gynecologic cancer is a critical concern in the field of women’s health, and traditional treatment methods have demonstrated limited efficacy for certain advanced and recurrent gynecologic cancers. In recent years, antibody–drug conjugate (ADC) therapy, as an emerging targeted approach, has gained increasing attention as a research hotspot. This review aims to elucidate the structure and mechanism of ADC drugs and explore their application and clinical research progress in gynecologic cancers such as ovarian cancer, cervical cancer, and endometrial cancer.
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关键词
Antibody–drug conjugate,Gynecologic cancer,Targeted therapy,Cervical cancer,Endometrial cancer,Ovarian cancer
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