Exploring Pharmacokinetic Variability of Palbociclib in HR+/HER2- Metastatic Breast Cancer: a Focus on Age, Renal Function, and Drug–gene Interactions

Elena Peruzzi,Bianca Posocco,Lorenzo Gerratana, Margherita Nuti,Marco Orleni,Sara Gagno,Elena De Mattia,Fabio Puglisi,Erika Cecchin,Giuseppe Toffoli,Rossana Roncato

Frontiers in Pharmacology（2024）

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palbociclib,metastatic breast cancer,minimum plasma concentration,pharmacokinetic variability,pharmacokinetic covariate,drug-drug interactions,drug-gene interaction,drug-drug-gene interactions

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