Intercellular Nanotube-Mediated Mitochondrial Transfer Enhances T Cell Metabolic Fitness and Antitumor Efficacy

Jeremy G. Baldwin,Christoph Heuser-Loy,Tanmoy Saha,Roland C. Schelker,Dragana Slavkovic-Lukic,Nicholas Strieder, Inmaculada Hernandez-Lopez, Nisha Rana,Markus Barden, Fabio Mastrogiovanni, Azucena Martin-Santos,Andrea Raimondi,Philip Brohawn,Brandon W. Higgs,Claudia Gebhard,Veena Kapoor,William G. Telford,Sanjivan Gautam,Maria Xydia,Philipp Beckhove, Sina Frischholz, Kilian Schober,Zacharias Kontarakis, Jacob E. Corn,Matteo Iannacone,Donato Inverso,Michael Rehli,Jessica Fioravanti,Shiladitya Sengupta,Luca Gattinoni

CELL（2024）

Cited 0|Views20

Key words

mitochondrial transfer,CD8+ T cells,nanotubes,cancer immunotherapy,bone marrow stromal cells,Talin 2,CAR T therapy,TCR-T therapy,TIL therapy,immune metabolism

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