Case Report: Artificial Thymic Organoids Facilitate Clinical Decisions for a Patient with a TP63 Variant and Severe Persistent T Cell Lymphopenia

Alevtina Gall,Marita Bosticardo, Stacey Ma,Karin Chen,Kayla Amini,Francesca Pala,Ottavia M. Delmonte,Tara Wenger,Michael Bamshad,John Sleasman, Matthew Blessing,Nicolai S. C. van Oers,Luigi D. Notarangelo,M. Teresa de la Morena

FRONTIERS IN IMMUNOLOGY（2024）

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TP63,T cell lymphopenia,artificial thymic organoids,ectrodactyly-ectodermal dysplasia clefting (EEC),ankyloblepharon-ectodermal defects-cleft lip/palate (AEC),cultured thymus tissue implantation (CTTI)

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