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CASPER: A Phase I Trial Combining Calaspargase Pegol-Mnkl and Cobimetinib in Pancreatic Cancer.

Charles D. Lopez,Adel Kardosh,Emerson Y. Chen,Guillaume Pegna,Alexander Guimaraes,Bryan Foster,Brian Brinkerhoff,Shaun M. Goodyear,Jeong-Youn Lim,Erin Taber,Brindha Rajagopalan, Exodus Edmerson,Johnson Vo, Katherine Nelson, Anna Jackson, Tasha Gingerich,Anne Fahlman, Christopher Lessenich, Francesca Fennell, Diane Ventura, Preeyam Roy,Dove Keith,Brett Sheppard,Jonathan R. Brody,Gordon B. Mills, Ze'ev A. Ronai,Rosalie C. Sears

FUTURE ONCOLOGY（2024）

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Key words

calaspargase pegol-mknl,cobimetinib,drug resistance,L-asparaginase,MEK inhibition,metabolic reprogramming,pancreatic cancer

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