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Metabolic Fate of the Natural Anticancer Agent Cucurbitacin B: an LC–MS/MS-enabled Profiling of Its Major Phase I and II Conjugates in Vivo

Wen-Ya Liu,Di Xu,Hui-Hui Meng, Cheng-Yao Wang,Xin Feng,Jun-Song Wang

Analytical and Bioanalytical Chemistry（2024）

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Key words
Cucurbitacin B,Drug metabolism,Metabolite identification,UHPLC-Q-TOF–MS/MS,Molecular networking,Antiproliferative activity
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