A Comprehensive Luminal Breast Cancer Patient-Derived Xenografts (PDX) Library to Capture Tumor Heterogeneity and Explore the Mechanisms of Resistance to CDK4/6 Inhibitors.

Ilenia Segatto,Maria Chiara Mattevi,Gian Luca Rampioni Vinciguerra, Nicole Crestan,Lorena Musco,Andrea Favero,Alessandra Dall'Acqua, Gabriele Di Giustino,Giorgia Mungo,Sara D'Andrea, Chiara Gava, Federica Ruggiero,Matteo Dugo,Lorenzo Gerratana,Fabio Puglisi,Samuele Massarut,Riccardo Bomben,Maurizio Callari,Tiziana Perin,Gustavo Baldassarre,Barbara Belletti

JOURNAL OF PATHOLOGY（2024）

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patient-derived xenograft,breast cancer,luminal breast cancer,estrogen receptor positive breast cancer,tumor heterogeneity,CDK4/6 inhibitor,drug resistance,endocrine therapy,tumor organoid,MTORC1

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