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Exploring the Role of PARP1 Inhibition in Enhancing Antibody–drug Conjugate Therapy for Acute Leukemias: Insights from DNA Damage Response Pathway Interactions

Andrea Ghelli Luserna di Rorà,Mouna Jandoubi,Antonella Padella,Anna Ferrari, Andrea Marranci, Cristina Mazzotti, Francesco Olimpico,Martina Ghetti,Lorenzo Ledda,Maria Teresa Bochicchio,Matteo Paganelli,Michele Zanoni,Alessandro Cafaro,Chiara Servili,Sara Galimberti,Michele Gottardi,Michela Rondoni,Mauro Endri, Daniela Onofrillo,Ernesta Audisio,Giovanni Marconi,Giorgia Simonetti,Giovanni Martinelli

JOURNAL OF TRANSLATIONAL MEDICINE（2024）

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关键词
Antibody–drug conjugates,PARP1 inhibition,DNA damage response pathway,Acute myeloid leukemia (AML),Acute lymphoblastic leukemia (ALL)
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