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Evaluation of Methotrexate Pharmacogenomic Variation to Predict Acute Neurotoxicity in Children with Acute Lymphoblastic Leukemia

Rachel D. Harris,Olga A. Taylor,M. Monica Gramatges,Amy E. Hughes,Mark Zobeck,Sandi Pruitt,M. Brooke Bernhardt,Ashley Chavana, Van Huynh,Kathleen Ludwig,Laura Klesse,Kenneth Heym,Timothy Griffin,Rodrigo Erana,Juan Carlos Bernini, Ashley Choi, Yuu Ohno,Melissa A. Richard,Alanna C. Morrison,Han Chen,Bing Yu,Philip J. Lupo,Karen Rabin,Michael E. Scheurer,Austin L. Brown

PHARMACOTHERAPY（2025）

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Key words
acute lymphoblastic leukemia,epidemiology,methotrexate,neurotoxicity,oncology,pediatrics,pharmacoepidemiology,pharmacogenomics
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